Think Global, Act Local

In the Philippines, many people would think that items made in other countries have better quality and are more desirable.More recently, with numerous goods coming from nearby also having built their reputation for similar or even betterquality – example, those Japan, Taiwan lately, China these now alsopopular. But it remains unusual we generally prefer local brands, i.e., Philippines.When comes to using scientific evidence as basis medical practice, should be argued high localdata is superior used. After all, derived our countrymen who may a different disease biology and/or natural history, sociocultural determinants, well clinical practices. It unfortunate, however, such data arenot always available. Even if exists, not easily accessible.
 this, issues of Acta Medica Philippina, see some efforts being by colleagues look intothis experience. They offer varied insights into how global diseases manifested locally: there differences weshould aware of?
 As far back 2006, Philippine Council Health Research Development (PCHRD) has already facilitatedthe creation National Unified Agenda (NUHRA) which reviewed every five years identifyresearch priorities Philippines.1 its latest iteration, 2017-2022 NUHRA prioritizes among others, holisticapproach health wellness aims produce geared towards application recognition traditional,sociocultural, alternative approaches health.2 The study Sanico Medina this issue highlights objective.It looked potential benefits risks an indigenous fermented rice wine called tapuy. Utilizing modernbiotechnology technique metagenomic sequencing, authors found significant presence probiotic bacteria thatcan explored applications. However, they detected harmful indicate theneed possible standardization fermentation practices.
 Acquired Immunodeficiency Syndrome (AIDS) long plagued landscape ever since was first describedin 1981.3 Because cases been described previously, AIDS increasing numbers, soon labeled anepidemic.4,5 HIV/AIDS epidemic fairly recent one.6-9 Sadly, country nowidentified one fastest growing HIV Western Pacific.10 Identifying perceptions generalcommunity, especially risk populations, can go way curtailing rising numbers.11 article Jamesand further evaluating knowledge, attitudes practices on prevention transmission ofHIV/AIDS college students Pampanga, Philippines. participants were low knowledge HIV/AIDS, but had good attitude toward positive individuals. recommended education HIV/AIDScould help control epidemic.
 Rogelio Santiago screening retinopathy patients gestational diabetes mellitus(GDM). Their did support done population. A previously reported GDM aprevalence 14% Philippines making worth addressing.12 On related note, several internationalguidelines define diagnosed.13 Obstetrics Gynecology Society advocates one-stepapproach (a single OGTT 75-g anhydrous glucose load fasting blood sugar ≥92 mg/dL, 2-hour level of<126 mg/dL). one-step approach convenient needs visit. report fromAustralia, follows process, showed at least 25% overdiagnosis consequent need forfurther testing patient anxiety goes it.14 An earlier US 50% women diagnosed withGDM compared two-step one.15 To fair, study, another alsoin Australia, no pregnancy outcomes between two approaches.16 Although localstudy identified numerical (e.g., primary caesarean section, large ageinfants, etc.) comparing criteria, statistically significant.13 Perhaps lookinto matter again larger cohorts. gears up Universal Healthcare, screeningfor become important.
 Arcilla, et al., validation foreign instruments assess treatment representsanother area where needed.17 Such seeks investigate whether instrument developed elsewhere willlikewise yield accurate comparable intended. BREAST-Q patient-reported outcomeinstrument designed evaluate undergoing types breast surgery.18 foundhigh internal consistency, test-retest reliability, acceptability. only moderate construct validity inthe Filipino cohort. Among findings, respondents difficulty understanding languagetranslations, negative reactions questions. recommend studies largernumber including undergone nipple reconstruction. initial results note bebetter interpret “sexual well-being” subscale separately because influence culture play.
 Manalili, al. hemoperfusion intervention COVID-19. highmortality length hospital stay. put perspective, period April September 2020,early pandemic when little relatively known about disease. Since then, know COVID-19,with vaccination anti-virals available could alter severity. December 2021, experts donot use COVID-19 mostly certainty ofevidence.19 option deterioration despite standard therapy includingtocilizumab however still suggested. published here interesting comparisonof group undergo hemoperfusion. certainly illustrates generating experience examining relevant practice/s setting.
 Case reports enhance describing profile management anuncommon rare presented atypically.20-22 We opportunity share four theserare cases. submitted Terencio, combination Guillain-Barre syndrome (GBS)allows us neurologic complications. continue gain importantinformation COVID-19, possibility GBS consequence clinicians anticipate additionaltreatments case. same true Ablaza Salonga-Quimpo abdominal dyskinesia(with colorful description “belly dancer dyskinesia”).
 Then case SOLAMEN syndrome, Maceda colleagues. This dramatic thatit presents disfigurement patient. Its nuanced requires multidisciplinary approachto address all affected body parts.23,24 Unfortunately, strong genetic component predilection tomalignancy require longer-term care. Another disease, X-linked dystonia parkinsonism, likewisereported Jamora others. movement disorder highly prevalent Panay Islandin Philippines.25-28 All so linked ancestry, suggesting founder andgenetic homogeneity. extremely globally, prevalence XDP 0.31 per 100,000; inPanay Island, 5.74 100,000. Ninety-five percent individuals males; average age 44 (20–70 years);and onset 39 (12–64 years).27 Cases descent othercountries.29 particular interest time procedure Unilateral TranscranialMagnetic Resonance-guided Focused Ultrasound Pallidothalamic Tractotomy tried condition; conditionwhich leads progressive disability definite treatment.27
 ones MedicaPhilippina.
 I am certain will insightful locally inthis journal. These testament able following highest standards,we act (and do studies) ways beneficial own community.
 Joven Jeremius Q. Tanchuco, MD, MHA Department Biochemistry Molecular Biology College Medicine, University Manila
 
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